Signals from the “conveyor belt”
Carlos F. Lopez, PhD, and colleagues propose a new “conveyor belt” mechanism for how cellular signaling is amplified, or strengthened, as signals are handed off from one enzyme to the next.
Carlos F. Lopez, PhD, and colleagues propose a new “conveyor belt” mechanism for how cellular signaling is amplified, or strengthened, as signals are handed off from one enzyme to the next.
Histone deacetylases (HDACs) are enzymes that modulate gene expression and have important roles in development and disease. HDAC inhibitors are active against lymphoma, and understanding the roles of specific HDACs is important for further therapeutic development. Scott Hiebert, Ph.