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Jeffrey Rathmell, Ph.D.

  • Co-Leader, Host-Tumor Interactions Research Program
  • Cornelius Vanderbilt Professor of Immunobiology
  • Professor of Pathology, Microbiology and Immunology
  • Director, Vanderbilt Center for Immunobiology

Phone

615-322-3234

Email

jeff.rathmell@vumc.org
Vanderbilt-Ingram Cancer Center
648-B Preston Research Building
2220 Pierce Ave
Nashville, TN 37232

Jeffrey Rathmell, Ph.D.

  • Co-Leader, Host-Tumor Interactions Research Program
  • Cornelius Vanderbilt Professor of Immunobiology
  • Professor of Pathology, Microbiology and Immunology
  • Director, Vanderbilt Center for Immunobiology

615-322-3234

jeff.rathmell@vumc.org

Vanderbilt-Ingram Cancer Center
648-B Preston Research Building
2220 Pierce Ave
Nashville, TN 37232

Profile

Education

  • Ph.D., Immunology, Stanford University, Stanford, California (1997)
  • B.S., Biology, University of Northern Iowa, Cedar Falls, Iowa (1991)

Research Emphasis

Immunometabolism in inflammatory disease, cancer, and anti-tumor immunity

Research Description

There has been a growing appreciation that metabolism is intimately linked to nearly all aspects of cell function and fate. The field of immunometabolism aims to understand how metabolic pathways are regulated in immune cells, how specific metabolic programs alter immune function, and how immunity in turn may influence metabolism. The Rathmell lab focuses on how metabolic pathways influence the function and fate of lymphocytes in inflammatory diseases and anti-tumor immunity. Our work is highly interdisciplinary in which we use animal models and genetic approaches in the fields of immunology, cancer biology, and cell metabolism to understand human disease. Ultimately the goals of these projects are to exploit the specific metabolic programs of each immune cell type or activation state to selectively impact effector lymphocytes in inflammatory diseases and cancer.

Publications

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