Breast_SPORE | Vanderbilt-Ingram Cancer Center

‘Multi-omics’ reveals treatment option for breast cancer subtype

Read more about ‘Multi-omics’ reveals treatment option for breast cancer subtype

In a multidisciplinary collaboration, researchers at Vanderbilt University Medical Center and the University of Miami Miller School of Medicine have identified a subtype of triple-negative breast cancer (TNBC) that appears to be able to escape detection by the immune system and evade immunotherapy.

Study identifies biomarker for breast cancer response to immunotherapy

Read more about Study identifies biomarker for breast cancer response to immunotherapy

A biomarker that has proven to be a predictor for response to immunotherapies in melanoma patients also has clinical relevance for breast cancer patients, according to a new study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

Grant strengthens breast cancer research efforts

Read more about Grant strengthens breast cancer research efforts

Breast cancer researchers at Vanderbilt-Ingram Cancer Center have secured a fourth round of continuous Specialized Program of Research Excellence funding.

A critical factor for wound healing

Read more about A critical factor for wound healing

Vanderbilt-Ingram Cancer Center scientists have discovered a role for a tumor suppressor protein in skin wound healing.

Breast cancer-killing RIG

Read more about Breast cancer-killing RIG

A recent study in the journal Cancer Research demonstrates that a RIG-I agonist has potent immunogenic and therapeutic effects in breast cancer.

Study seeks to boost breast tumor immune response

Read more about Study seeks to boost breast tumor immune response

Targeting specific molecules in breast tumors, called methylating agents, can turn up the immune response, potentially making tumors responsive to immunotherapy, suggests a new study published in Nature Communications.

Breast SPORE News

October 25, 2023

VUMC to help engage more study participants in research decisions

Human research will be more equitable, inclusive and stronger if the people who are participants in studies also help plan and guide the direction of those studies.

November 17, 2023

Tumor antigens key to improving cancer immunotherapy study

Vanderbilt researchers are working to better design immune therapies that attack tumors without also attacking healthy normal tissue in patients.

November 17, 2023

Vanderbilts Dr. W. Kimryn Rathmell to be appointed director of the National Cancer Institute

Kimryn Rathmell MD PhD MMHC the Hugh Jackson Professor of Medicine and chair of the Department of Medicine at Vanderbilt University Medical Center will be appointed Director of the National Cancer Institute.

More Breast SPORE News

Study to test combination therapy for breast cancer

Read more about Study to test combination therapy for breast cancer

Vanderbilt-Ingram Cancer Center has received $2.3 million to fund a clinical research trial testing a combination of three immunotherapy compounds for patients with a specific type of advanced breast cancer.

Study explores how some breast cancers resist treatment

Read more about Study explores how some breast cancers resist treatment

A targeted therapy for triple-negative breast cancer (TNBC), the most aggressive form of breast cancer, has shown potential promise in a recently published study. TNBC is the only type of breast cancer for which there are no currently approved targeted therapies. The new study led by Vanderbilt-Ingram Cancer Center (VICC) investigators has identified gene alterations […]

Study details rare heart risk of certain cancer therapies

Read more about Study details rare heart risk of certain cancer therapies

Combination therapy using two approved immunotherapy drugs for cancer treatment may cause rare and sometimes fatal cardiac side effects linked to an unexpected immune response. In a study led by Vanderbilt University Medical Center (VUMC) investigators and published in the Nov. 3 issue of the New England Journal of Medicine, researchers describe two cases of […]

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